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White Paper · Clinical Study

Craniofacial Changes after Combined Atlas-Orthogonal and Biomimetic Oral Appliance Therapy

A research article by Dr. Dave Singh, Dr. Chris Chapman, and Dr. Myles Preble

Atlas Orthogonal + Oral Appliance: Craniofacial Study | Cerebral — figure
68.2%
overall improvement in craniofacial alignment
22.7 → 6.0 discrepancy score
11
adults treated
average age 39.5
2-stage
atlas correction, then oral appliance
measured at each stage

Advancing Craniofacial Alignment and Posture

Head and neck alignment play a crucial role in overall health, yet traditional chiropractic or dental approaches often address these issues independently. In a groundbreaking study, Dr. G. Dave Singh, Dr. Chris Chapman, and Dr. Myles Preble explore the combined effects of atlas orthogonal (AO) chiropractic adjustments and biomimetic oral appliance therapy (BOAT) in their paper, Craniofacial Changes after Combined Atlas-Orthogonal and Biomimetic Oral Appliance Therapy.

Dr. Singh has stayed on the cutting edge of innovation in biomimetic oral appliances, pushing the field of dentistry and orthodontics to new heights. Dr. Chapman is a pioneer in the upper cervical world, bridging the gap of clinical care between airway orthodontics and upper cervical chiropractic care. As one of our esteemed colleagues, Dr. Chapman carries the prestigious title of Diplomate of Chiropractic Craniocervical Junction Procedures, one of only approximately 80 worldwide. Through his efforts and ongoing collaboration between these worlds, we have seen substantial advancements in cranio-cervical and craniofacial stability, leading to significant improvements in clinical outcomes.

This study builds on the collective expertise of these three thought leaders, offering a multidisciplinary solution that significantly improves craniofacial alignment and provides a new perspective on addressing structural and neurological health.

How the Study Was Conducted

Eleven adults (average age 39.5) with atlas subluxations and malocclusions were evaluated. Participants first underwent AO adjustments, targeting upper cervical misalignment. Following these adjustments, they were fitted with a biomimetic oral appliance (DNA appliance®), designed to optimize craniofacial and dental structure. Radiographic assessments measured alignment changes at three stages: pre-treatment (T0), post-AO adjustment (T1), and after oral appliance therapy (T2). This systematic approach allowed researchers to evaluate the isolated and combined effects of each therapy on craniofacial alignment.

Key Findings and Implications

The study revealed that combining AO adjustments with BOAT created a powerful synergy for improving craniofacial alignment. Participants experienced a mean improvement of 68.2% in craniofacial alignment after the combined therapy. Specific parameters such as atlas cephalic displacement, cervical spine angles, and axis rotation showed significant enhancements. For example:

Overall craniofacial misalignment (lower is better)
Overall craniofacial misalignment (lower is better)Bar chart showing overall craniofacial misalignment score dropping across three stages: 22.7 at baseline, 9.7 after atlas correction, and 6.0 after the oral appliance.051015202522.7Baseline9.7After atlascorrection6After oralappliance
Overall misalignment fell 68.2% — from 22.7 to 6.0 — with the combined therapy outperforming atlas correction alone.
View the data
Overall craniofacial misalignment (lower is better) — misalignment score
BaselineAfter atlas correctionAfter oral appliance
Misalignment22.79.76
  • Atlas cephalic displacement decreased from 2.50 mm at baseline to 1.10 mm after AO adjustments and further to 0.50 mm after BOAT.
  • Axis (C2) rotation improved from 6.60° at baseline to 2.80° after AO adjustments and to 1.50° with the combined therapy.
  • Cervical spine-atlas angular rotation improved from 3.10° at baseline to 1.60° after AO adjustments and further to 0.60° after BOAT.
Component measurements at each stage
Structural measureBaselineAfter atlas correctionAfter oral appliance
Atlas lateral displacement (mm)2.501.100.50
Axis (C2) rotation (°)6.602.801.50
Cervical spine–atlas rotation (°)3.101.600.60
Each individual structural measure improved at every stage of care.

These structural improvements suggest the combination of AO adjustments and BOAT provides greater benefits than either therapy alone. Beyond alignment, the combined therapy addresses underlying compensation mechanisms that may enhance overall postural stability, airway function, and neurological outcomes. This evidence emphasizes the importance of integrating care when treating complex conditions like craniofacial and upper cervical misalignment.

A New Perspective on Structural Health

This study reinforces the idea that structural and neurological health is best addressed through a multidisciplinary approach. Combining AO adjustments with BOAT not only optimized craniofacial alignment but also highlighted how different healthcare specialties can work together to address root causes of structural imbalances.

At Cerebral, our primary goal is to uncover the root cause or causes of a patient’s problem and tailor a solution to their unique needs. This may involve precise upper cervical care alone or collaborating with other healthcare providers, such as airway orthodontists, for a comprehensive treatment plan. The more we explore multidisciplinary care for complex conditions, the more we find opportunities to achieve long-term structural stability and improved neurological outcomes—outcomes that might not be possible with isolated approaches. This research exemplifies how integrating expertise can lead to transformative results for patients.

Read the Full Article

For the complete methods, findings, and clinical detail, we encourage you to read the original publication. Access the full article here.

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Common Questions

Questions about this research

What did the craniofacial study find?

In 11 adults, combining atlas orthogonal upper cervical care with a biomimetic oral appliance reduced overall craniofacial misalignment by 68.2%, with measurable gains at every stage of treatment.

Is upper cervical care related to the jaw and bite?

Yes. The jaw, bite, and airway sit directly below the skull and upper neck, so the alignment of the atlas and the position of the jaw influence each other — which is why combining the two therapies outperformed either one alone.

What is a biomimetic oral appliance?

It is a removable dental appliance (the study used the DNA appliance) designed to gently guide the position and development of the jaws and craniofacial structures over time, improving the bite and airway.

Why combine chiropractic and orthodontic care?

Because structural problems rarely live in one place. Correcting the upper neck first, then optimizing the bite and airway, addressed compensations that neither discipline could fully resolve on its own.

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About the Reviewer
Dr. Chris Slininger, DC, DCCJP
Craniocervical Specialist

Dr. Slininger focuses heavily on complex neurological conditions and advanced spinal challenges such as headaches, migraines, dizziness, vertigo, concussion, mTBI and more.

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